well first, be very care full about taking out the old one and putting the new one in. you could damage your mobo and your processor if your not careful.
then for the bios. what i do is just take out the coin cell battery and leave it out for 10 seconds. then put it back in. then your bios are reset. that will also undo any overclocks you had done. but ya, thats what i have always done, and it seemed to work well for me. make sure you also install any drivers and software needed.
Edit: you can also find videos of this on youtube prolly.